The 5th Joint Workshop on Information Security (JWIS 2010) will be held in Guangzhou, China on August 5(Thursday) - 6(Friday), 2010. The focus of this workshop is on the technical and practical aspects of the security applications. The workshop will serve as a forum to present new results from the academic research community as well as from the industry. Original papers are solicited for submission to JWIS 2010. In addition, several distinguished security experts will be invited to give technical talks.